Davis's Drug Guide
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metoprolol

Implementation

  • High Alert: IV vasoactive medications are inherently dangerous. Before administering intravenously, have second practitioner independently check original order and dose calculations.
  • High Alert: Do not confuse Toprol-XL (metoprolol) with Topamax (topiramate). Do not confuse Lopressor with Lyrica. Do not confuse metoprolol tartrate with metoprolol succinate.
  • PO: Take apical pulse before administering. If <50 bpm or if arrhythmia occurs, withhold medication and notify health care professional.
    • Administer metoprolol with meals or directly after eating.
    • Extended-release tablets should be swallowed whole; do not break, crush, or chew.

IV Administration

  • Direct IV: Diluent: Administer undiluted. Concentration: 1 mg/mL.
  • Rate: Administer over 1 min.
  • Y-Site Compatibility
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  • Y-Site Incompatibility
    • allopruinol
    • amphotericin B cholesteryl
    • amphotericin B colloidal
    • amphotericin B lipid complex
    • dantrolene
    • diazepam
    • diazoxide
    • pantoprazole
    • phenytoin
    • trimethoprim/sulfamethoxazole

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